How does CBD help with convulsive seizures?

How does CBD help with convulsive seizures?
A 2017 clinical trial published in The New England Journal of medicine discovered persons with Dravet syndrome, a type of epilepsy, experienced a significant reduction in convulsive-seizure frequency from the use of a cannabidiol solution. The study was conducted by NYU and lead to the approval of a pharmaceutical CBD solution called Epidiolex by the FDA. There is now evidence from several studies that CBD used as a supplement improves seizure control in patients with specific epilepsy syndromes. From this collected data, it can be deduced cannabinoids play a considerable role in synaptic transmission and the regulation of neuronal firing.
CBD contributes to lowering seizure activity in convulsive syndromes and psychosis/ schizophrenia by indirectly modulating Glutamate NMDAR activity. These receptors are integral in many neurological disorders, displaying hyperactivity in convulsive disorders like epilepsy. CBD is becoming increasingly popular as a substitute for treatments that modify NMDAR & GPCR interactions as these can compromise neuronal survival.
CBD reduced seizures
Cannabinoids can inhibit the overactivation of glutamate NMDAR receptors and hence reduce the occurrence of convulsive episodes; Exocannabinoid (consumed from our oils), behaving through NMDAR-recruited CB1R-NMDAR complexes would reduce excitatory signalling. The endocannabinoid system is postulated to play a role in seizure frequency, external modulation of this system can prevent or modulate seizure activity.
Our oils are ISO-certified lab tested and contain premium CBD extracts, farmed using sustainable practices. The supplementation of CBD can be a viable alternative to synthetic seizure control medication and we are here to provide you with oils you can trust – click here to shop our collection and use code: site15 for 15% off your entire basket; our vision is to expose the benefits of CBD to all.

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