CBD as a remedy for chronic pain

CBD as a remedy for chronic pain
Cannabidiol is a chemical with potential often not explored by many due to prejudice and negative connotations associated with the plant from which it is derived from. This short article will attempt to highlight its power pertaining to pain management, consulting a few scientific studies to support any points made. (Don’t worry, we’ll keep it short & sweet!) 
Chronic pain is an enduring issue within the field of medicine as its treatment isn’t clear-cut nor guaranteed. The hunt for new age painkillers is always imminent as virtually every pharmaceutical compound / synthetic molecule on the market has adverse side effects. There is strong evidence suggesting that non-psychoactive cannabinoids, which occur naturally in hemp plants, can also alleviate chronic inflammatory and neuropathic pain – without any undesirable side-effects.
Glycine receptors (GlyRs) are a critical target for cannabinoids in the CNS [Central nervous system] in relation to alleviating pain; CBD and other cannabinoids (a large proportion & variety of which can be found in ‘full-spectrum’ hemp oils) can increase the power of glycine currents (I[Gly]) in native neurons. This is an important phenomenon as GlyRs are widely considered to play an imperative role in blocking the detection of pain/ injurious stimulus by sensory neurons.
 
CBD Pain Cure
GlyRs comprise of 4 isoforms of ‘a subunits’; the a3 subunits are known to participate in the transmission of pain-related (nociceptive) information. Hence the treatment of pain is largely mediated through an a3 GlyR-dependant mechanism.
In conclusion glycinergic cannabinoids (including CBD) supress inflammatory pain, proving efficacious in creating an analgesic effect by potentiating the aforementioned glycine currents in the spinal chord neurons. In a past study, researchers observed a strong interaction between CBD and the S296 domain within the a3-GlyR sites; this ascertains the cannabinoids analgesic property.
 Here at Diem Botanics, we offer only full-spectrum oils and creams to extract the most cannabinoids to help facilitate this pain-killing effect by increasing the power of glycine currents. Click here to be directed to our shop where you can purchase our competitively-priced premium oils / sprays / creams of varying strengths to help you enhance your quality of life by joining your fight against pain.

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